Charlie Musselwhite (born January 31, 1944 in Kosciusko, Mississippi) is an American blues-harp player and bandleader, one of the non-African-American bluesmen who came to prominence in the early 1960s, along with Mike Bloomfield and Paul Butterfield. Though he has often been identified as a "white bluesman", he claims Native American and Thai heritage.

Childhood
In true bluesman fashion, Musselwhite then took off in search of the rumored "big-paying factory jobs" up the "Hillbilly Highway", legendary Highway 51 to Chicago, where he continued his education on the South Side, making the acquaintance of even more legends including Lew Soloff, Muddy Waters, Junior Wells, Sonny Boy Williamson, Buddy Guy, Howlin' Wolf, Little Walter, and Big Walter Horton. Musselwhite immersed himself completely in the musical life, living in the basement of, and occasionally working at Jazz Record Mart (the record store operated by Delmark Records founder Bob Koester) with Big Joe Williams and working as a driver for an exterminator, which allowed him to observe what was happening around the city's clubs and bars. He spent his time hanging out at the Jazz Record Mart at the corner of State and Grand and the nearby bar, Mr. Joe's, with the city's blues musicians, and sitting in with Big Joe Williams and others in the clubs, playing for tips. There he forged a lifelong friendship with John Lee Hooker; though Hooker lived in Detroit, Michigan, the two often visiting each other, and Hooker serving as best man at Musselwhite's wedding. Gradually Musselwhite became well known around town.
In time, Musselwhite led his own blues band, and, after Elektra Records' success with Paul Butterfield, he released the classic
His past two albums, Sanctuary and Delta Hardware have both been released on Real World Records.